Some effects of Ca-free choline-Ringer solution on frog skeletal muscle
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چکیده
منابع مشابه
Permeability of Frog Skeletal Muscle Cells to Choline
Using choline-methyl-C(14) as a tracer, it has been shown that choline(+) penetrates into the cells of resting frog skeletal muscle at a rate similar to that of Na(+), and that it escapes from these cells much more slowly than does Na(+). Some implications of these findings are discussed.
متن کاملPermeability of Frog Cells to Choline Skeletal Muscle
Using choline-methyl-C 14 as a tracer, it has been shown that choline + penetrates into the ceils of resting frog skeletal muscle at a rate similar to that of Na +, and that it escapes from these cells much more slowly than does Na +. Some implications of these findings are discussed. Permeability of Frog Skeletal Muscle Cells to Choline It is generally believed that choline ions do not penetra...
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Ca 2 1 sparks were first detected as spontaneous, highly localized elevations of Ca 2 1 indicator fluorescence in confocal microscope images of rat cardiac myocytes studied under resting conditions (Cheng et al., 1993). It was immediately suggested that these events are likely to reflect the localized release of Ca 2 1 from a small cluster of sarcoplasmic reticulum (SR) Ca 2 1 release channels ...
متن کاملPROLONGED ACTION POTENTIAL OF GLYCEROL-TREATED SKELETAL MUSCLE FIBRES OF FROGS IN Ca-FREE EGTA SOLUTION
In glycerol-treated sartorius muscle fibres, membranes were depolarized to about-30 mV when muscle fibres were perfused with Ca-free solution containing 2 mM EGTA. Under such a condition, muscle fibres were able to produce not only an initial spike potential (initial SP) but also a following slow depolarizing response (slow DR) forming a plateau phase by cathodal current pulse when membrane was...
متن کاملEffects of Azumolene on Ca Sparks in Skeletal Muscle Fibers
Azumolene is an analog of dantrolene, the only approved medicine for treatment of malignant hyperthermia (MH). The pharmacological mechanism of these drugs is to inhibit skeletal muscle sarcoplasmic reticulum (SR) Ca release by modulating the activity of the SR ryanodine receptor (RyR) Ca release channel. To investigate the effects of azumolene on SR Ca channel gating within skeletal muscle fib...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1963
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1963.sp007091